When: Friday May 14, 20:00 GMT
How to watch: Sky Sports
Manchester City will head to St James' Park on Friday night with the Premier League title in the bag, and what a well-deserved crown it is.
The Citizens had their triumph confirmed on Tuesday night courtesy of city rivals Manchester United losing to Leicester, although few expected the trophy to end up anywhere other than The Etihad regardless.
Newcastle can also go into the game without pressure after Fulham's defeat to Burnley confirmed another season of Premier League soccer on Tyneside.
Last Three meetings
Man City 2-0 Newcastle (December 26, 2020)
When the two sides met on Boxing Day last year, it was more routine than rout for Manchester City.
Ilkay Gundogan handed them the lead inside 15 minutes, and they were rarely troubled from that point onwards.
Ferran Torres added a second shortly after the break, while the Magpies struggled to land a significant punch on Pep Guardiola and his troops.
Man City 5-0 Newcastle (July 8, 2020)
If the Manchester City win on Boxing Day 2020 was routine, then this one was definitely more of a rout.
It was also a landmark day for the history books. They became the first English top division team since Everton in 1984-85 to have five players to score ten or more goals in single season, and the first Premier League club to win 30 games in the competition by five or more goals.
Newcastle 2-2 Man City (November 30, 2019)
If Newcastle need to take heart form any match ahead of this fixture, they could do worse than to look at this one.
Steve Bruce's men managed to dig out a fine point on Tyneside after twice trailing to the Citizens.
Raheem Sterling had the visitors ahead midway through the first half, but Jetro Williams hit an instant equaliser.
When Kevin De Bruyne put City ahead again six minutes from time it looked all over, but Shelvey had other ideas.
Premier League head-to-head
Newcastle wins: 8
Man City wins: 25
Newcastle goals: 37
Man City goals: 79
How you judge Newcastle's season probably depends upon your perspective or expectations.
Steve Bruce has delivered 39 points in 35 games and secured Premier League safety. That's clearly good enough for Mike Ashley, and Bruce himself, but Newcastle fans understandably harbour hopes of at least aspiring to better.
In truth, they haven't shown any evidence of doing that under Bruce, and when that is coupled with the meek manner which has defined too many of their performances this season, it is easy to see why there is discontent among the supporters.
However, it is just as fair to say that on their day Newcastle are capable of turning on some style against anyone, as their recent 4-2 away win at Leicester City proves.
By contrast, Manchester City have been the picture of consistency this season, and they arguably look better than ever before.
The Citizens have scored the most goals in the Premier League, conceded the fewest, and dominate just about every stat you'd want to.
Inevitably, some attention will have now turned to the Champions League final. How that manifests itself on the pitch is anyone's guess, though.
You could say players will be extra motivated to play for places in the final, but often players drop their intensity a touch out of fear of injury.
Either way, Guardiola's men will be the favourites to win this one, as they are for probably any match they play right now.
Newcastle are without top striker Callum Wilson for the rest of the season due to injury, so it's tough to see where they might get a goal from here.
It might take a bit of individual magic to break through, and that generally means looking to Allan Saint-Maximin. He is 11/2 to score anytime and that looks like decent value, especially if Man City's tackling intensity has dropped a touch.
For Man City, if there is one player who is perhaps immune from any potential drop in motivation levels it is Phil Foden.
He is still playing with that youthful exuberance, and he will also know a strong end to the season will make him impossible for Gareth Southgate to ignore at this summer's European Championships.
You can back him to open the game's scoring at 5/1 with Bet365.