Lazio and Roma are expected to play out another chaotic Rome Derby on Sunday afternoon (1700 GMT) and football tipster Sergiu Baltuta expects their top scorers to strike.
Immobile started his youth career with Sorrento before moving to Juventus, where he made his senior breakthrough.
However, with his playing time limited at the Old Lady, Immobile moved on to Genoa permanently following loan spells at Siena, Grosseto and Pescara. He then made the switch to Torino, where his talent truly started to show.
Shining at Torino
Immobile joined Torino on July 12, 2013, and made a scoring debut in the first round of the Coppa Italia against his former team, Pescara.
Immobile picked up an assist on his Serie A debut for Torino and then soon got off the mark as far as goalscoring is concerned, finding the back of the net in a 2-2 draw with Sampdoria on October 7, 2013.
This goal proved to be the first of many for Immobile, who had previously endured a lengthy goal drought lasting nearly an entire year.
Immobile finished the season as the highest goalscorer in Serie A with 22 to his name. He became the first Torino player to win the Capocannoniere since Francesco Graziani in the 1976/77 campaign.
Struggling at Borussia Dortmund
On June 2, 2014, Immobile was announced as a Borussia Dortmund player. At the time, there was a dispute over the co-ownership agreement that Torino and Juventus had, but ultimately, his transfer to Dortmund went ahead.
"With Ciro Immobile we are getting a versatile and dynamic striker who has established himself in a top European league in an impressive manner. His outstanding qualities fit perfectly with the profile required by Borussia Dortmund," said Borussia Dortmund sporting director Michael Zorc.
However, Immobile's 2014/15 season at Borussia Dortmund was disappointing overall, as he scored just 10 goals in 34 appearances, including only three in 24 Bundesliga games.
Even though Immobile struggled for form at Dortmund, the Italian striker quickly came to the defence of Jurgen Klopp, when the German manager came under fire during a poor run during the 2014/15 campaign.
Speaking of his time in Dortmund, Immobile fondly recalled the experience of working under the now-Liverpool manager. "Klopp leaves something behind for you. You don't forget someone like him," Immobile told Sport Bild.
European Golden Shoe at Lazio
In 2017/18, Immobile went from strength to strength, scoring 29 goals in 33 Serie A appearances and sharing the Capocannoniere with Mauro Icardi. Overall, Immobile scored 41 goals in 47 appearances throughout the course of the season.
However, in 2019/20, Immobile set the all-time Serie A goals record with 36. He also won the European Golden Shoe. In all competitions, Immobile scored 39 goals in 44 appearances.
Italian national team
He received his first international call-up under Cesare Prandelli and subsequently featured in a 1-0 friendly defeat to then-European and world champions Spain.
Immobile was in Italy's squad for the 2014 FIFA World Cup and for Euro 2016.
In an interview with World Soccer, he reflected on the disappointment of Italy missing out on the 2018 FIFA World Cup in Russia.
"One of the darkest moments of my career. As is often the case in life, we learned our lessons from it so that such a disappointment would not happen again. Under [current boss Roberto] Mancini we have been doing a fantastic job. The tifosi are really excited about the Azzurri again," he said.
Entering 2020, Immobile had scored just 10 goals in 42 appearances for the national side. However, he scored in 3-0 victories over Turkey and Switzerland in Italy's first two matches of Euro 2020 to take his 2021 tally to five goals in six games.
"On behalf of the whole team, I wanted to dedicate our win and my goal to David and Daniel, the two angels who are no longer with us," said Immobile, as quoted by the Daily Mail. "It's our duty to embrace them, wherever they are."
Salary Sport report that Immobile earns £130,000 per week at Lazio.