Lazio and Juventus meet in the second leg of the Coppa Italia semi-final this Tuesday night at the Stadio Olimpico in Rome.
Roma face Bologna on Monday evening knowing a win over their rivals will increase their chances of a Champions League return, given that Serie A will likely have five spots next season (1730 BST).
Real Madrid play host to Barcelona in round 32 of La Liga on Sunday night at the Santiago Bernabeu (2000 BST), as Los Blancos look to nail down another title.
Roma and AC Milan will renew rivalries in the Europa League on Thursday (2000 BST) with the hosts defending a slender 1-0 lead at Stadio Olimpico.
The second leg of the Europa League quarter-final between Marseille and Benfica will take place on Thursday (2000 BST) at the Stade Velodrome.
Borussia Dortmund will be looking to cut their losses as they take on Atletico Madrid in the second leg of their Champions League quarter-final this Tuesday night (2000 BST).
Greek club Olympiacos will square up to Turkish giants Fenerbache in the Europa Conference League on Thursday evening (1745 BST).
AC Milan haven’t lost to Roma in almost five years and should extend that record in the Europa League on Thursday (2000 BST).
Benfica should seize the initiative when they play host to Marseille in the Europa League quarter-finals on Thursday (2000 BST).
PSG are aiming to win the French Cup for the first time in three years but they’ll need to find a way past Rennes in Wednesday’s semi-final.