The former world No.1 took to social media to announce his plans to help Ukraine amid the ongoing invasion by Russia.
The 34-year-old revealed that his partnership with Unicef will help provide children with medical supplies and educational needs.
Murray's statement on Twitter read: "Over 7.5m children are at risk with the escalating conflict in Ukraine, so I'm working with Unicef to help provide urgent medical supplies and early childhood development kits.
"It's vital education continues, so Unicef is working to enable access to learning for displaced children, as well as supporting the rehabilitation of damaged schools, together with replacement equipment and furniture.
"I'm going to be donating my earnings from my prize money for the rest of the year, but anyone in the UK can support Unicef's humanitarian response by donating to our appeal"
The remainder of the tennis world has joined Murray in supporting Ukraine, and the sport's governing bodies joined together on Tuesday to announce a donation of £530,000 to help humanitarian efforts in Ukraine and support the Ukraine Tennis Federation.
Ukrainian star Dayana Yastremska also donated her prize money from the Lyon Open to help her home country, with the 21-year-old reaching the final in remarkable circumstances last week.
Murray recently reunited with former coach Ivan Lendl earlier this week, and will hope to return to winning ways under the Czechoslovakian after the duo combined to win two Wimbledon titles and a US open title back in 2012.
The Scotsman is expected to stay in the US after upcoming tournaments in Indian Wells and Miami later this month, so he can extensively train with Lendl ahead of the grass season.
With Murray still recovering from his hip and groin injuries, he decided with new coach Lendl to skip the clay season in order to focus on upcoming grass-court tournaments.