When: Saturday, April 10, 17:30 GMT
How to watch: Sky Sports Main Event
Following a goalless draw with Leeds, the Blues then spectacularly fell apart in a home clash with West Brom, losing 5-2.
Tuchel's men responded well in the Champions League with an impressive away win over FC Porto however, the question remains whether they can do the same this weekend in the Premier League.
The pressure is certainly on. Chelsea spent big in the summer and while Tuchel's arrival came half-way though the season, the expectation of a top four finish remains in place.
For Crystal Palace, this is an opportunity to move above Wolves into 12th spot. Roy Hodgson's men have enjoyed a steady campaign and a mid-table finish isn't beyond them.
Last Three Matches
Chelsea 4-0 Crystal Palace (Premier League - October 3, 2020)
Last time these two clubs met in the Premier League, it was certainly a tale of two very different halves.
The first 45 minutes was rather frustrating - not only for the players but also for the viewers. With only two shots on goal, this was not exactly an instant classic.
However, Ben Chilwell's goal straight after the interval really livened things up. Chelsea used their newly found momentum and soon scored a second courtesy of Kurt Zouma.
Things went from bad to worse for Palace as Hodgson's men conceded two late penalties. Jorginho converted them both as the three points stayed at Stamford Bridge.
Crystal Palace 2-3 Chelsea (Premier League - July 7, 2020)
This fixture was much closely contested when the two clubs last met at Selhurst Park.
Chelsea scored a couple of early goals through Olivier Giroud and Christian Pulisic however, the Blues were pegged back by a Wilfried Zaha strike just before half time.
Tammy Abraham regained Chelsea's two-goal lead on the 71st minute mark but Christian Benteke got the Eagles within one just a minute later.
In spite of a spirited effort, the Eagles were unable to find the equaliser and Chelsea returned to the Bridge with the full set of points.
Chelsea 2-0 Crystal Palace (Premier League - November 9, 2019)
Chelsea were in full control when the two clubs clashed at Stamford Bridge towards the end of 2019.
With 60% possession and over 20 attempts throughout the 90 minutes, Frank Lampard certainly had a reason to be happy.
Second half goals from Tammy Abraham and Christian Pulisic sealed the victory for the Blues as they maintained their push for Champions League places.
Last ten Premier League head-to-head games
Crystal Palace wins: 2
Chelsea wins: 8
Crystal Palace goals: 8
Chelsea goals: 18
Chelsea's race for Champions League football
Chelsea have eight Premier League games remaining to try and secure a top four finish. The Blues are still in the Champions League and according to some, they may even be one of the favourites to win the competition this season.
Despite this, Thomas Tuchel's men would rather secure a top four spot then rest all their hopes on winning the biggest club competition in Europe.
With some tough league games ahead, Chelsea cannot afford to lose points and a win over Palace is paramount if they are to remain in the hunt for that all-important top four finish.
Eight Premier League games left for the Blues
Crystal Palace (A)
West Ham (A)
Man City (A)
Aston Villa (A)
Can Palace end Chelsea losing run?
It's fair to say that Crystal Palace have not enjoyed many of their recent games with Chelsea. In fact, the Blues have won all six of their most recent encounters.
Generally, Palace are in decent form heading into this fixture having lost just one of their last six matches. The question is, do they have enough fire power to threaten Tuchel's Blues?
Wilfried Zaha will have to be on top of his game if Palace are to threaten their opponents. The Ivory Coast international has bagged nine goals this season; three more than Chelsea's Mason Mount and four more than Timo Werner.
The aforementioned Wilfried Zaha is certainly one man to watch. However, from a betting perspective, our recommendation is to back Chelsea's in-form midfielder, Mount.
The England international has scored three goals from his last four appearances and is enjoying a brilliant run of form.
At the price of 13/5, he's certainly worth a shot.