Fury, who resides in the town, will sponsor the home and away playing shorts for the 2022/23 season.
Morecambe were promoted to League One in 2021 after winning the League Two play-off final against Newport County at Wembley.
In their first ever season in the third division, the club managed to avoid relegation as they finished 19th.
The side will now be boosted by the most famous resident of the northern town. Fury will have his Gypsy King brand feature on playing shorts, with a further announcement still to come.
Head of Commercial Martin Thomas said: "We have a great relationship with Tyson and are proud to wear his Gypsy King brand on the first-team shorts for the forthcoming campaign.
"Tyson is a fantastic ambassador for the Morecambe area and it's fantastic to have him onboard. Tyson is one of the most recognisable names in the world of sport, and will bring worldwide recognition Club.
"He will join a ever-growing list of commercial partners, alongside both local and national brands as well as local businesses the Club have signed in recent seasons. We now have a huge reach across the globe, with further presence on a worldwide stage due to this partnership."
Tyson Fury added: "I love the Morecambe area and it is a pleasure to be able to support my local club."