The Spaniard is expected to join Chelsea in a deal worth upwards of £62million, meaning City will have to take their hunt for a left-back elsewhere.
Pep Guardiola is desperate to fill the void left by the departure of Oleksandr Zinchenko, who completed his summer move to Arsenal.
When asked whether there was any imminent transfer news, the City boss said: "Nothing special. It is the same. We will see. We still have lots of days until the end of the month. We will see.
"There are a lot of players all around the world and a lot of them can fit in perfectly the way we are as a team, but at the same time transfers are always difficult.
"Selling is more difficult than buying at the same time. Sometimes it works, sometimes it doesn't. It can be possible, it cannot be possible."
The Citizens kick off the defence of their title against West Ham on Sunday, with the club aiming for a fifth league crown in six seasons.
Guardiola reckons this campaign will be the toughest ever.
"Every year I have the feeling that this season is harder," he said. "I think that next season cannot be harder and it's harder.
"Everyone is getting better, every club every owner invests. Many teams do it and do it well, the quality is there and the managers are exceptional.
"That's why it is exciting and that's why the Premier League is the best."