Manchester United head into their potentially season-defining clash against Liverpool with a long list of injuries which includes Edinson Cavani, Luke Shaw, Raphael Varane, Fred and Scott McTominay.
Many feared Bruno Fernandes could've followed his teammates onto the sidelines after being involved in a car crash on Monday morning. However, in his pre-match press conference, Rangnick revealed that his star midfielder will be available for the trip to Anfield.
With Tottenham and Arsenal slipping up at the weekend, the Red Devils improved their top-four hopes courtesy of a 3-2 victory over Norwich City.
Should Rangnick's men make it back-to-back league wins on Tuesday night, United would jump back into fourth spot - if only for the night.
Trouble is, picking up a victory over Jurgen Klopp's machine would be hard enough with a fully fit squad. Instead, Rangnick will have to use every ounce of his managerial experience if he is to conjure up a winning formula.
"It's up to us," the interim manager said. "We definitely will travel there tomorrow and try to get the three points. This is what it's all about.
"It's not about the situation they're in, it's about our own situation.
"After last weekend's results, we are still in the race for number four but in order to stay in that race we have to win almost every game. To start with, tomorrow.
"Although we might be the underdogs for most people, we still know that if we raise our level, if we play a top performance ourselves, we have a chance to get three points there and this will be our ambition and our goal for tomorrow."
Back in October, the Red Devils suffered an embarrassing 5-0 defeat in the reverse fixture. With the Reds in high-flying form and United unable to field their strongest team, a repeat is not out of the question.
Nevertheless, Rangnick will be buoyed by the news about playmaker Fernandes. Nobody is said to have suffered serious injuries from the car crash, including the 27-year-old who trained with the team later that day.
The United boss added: "Yes, he was training with the team. Obviously the accident happened on the way to Carrington but as far as I know nobody was injured.
"He trained with the team and he was OK. That's why I think he will also be OK for tomorrow."