The French winger has been out of action since January due to a left thigh injury, but his recovery has been progressing well.
According to journalist Adria Albets, Dembele's return to action is still difficult but not entirely ruled out for the Copa del Rey semi-final second leg. The Catalans hold a 1-0 advantage from the first leg and need at least a draw to secure a place in the finals.
Barcelona have been rocked by injuries in recent weeks, with Pedri, Andreas Christensen, and Frenkie de Jong all missing out on crucial fixtures. Dembele's return would provide a massive boost to Xavi Hernandez's side, who have struggled to find their attacking rhythm in his absence.
The 25-year-old forward has been working tirelessly at the club's Ciutat de Esportiva complex to complete his recovery at the earliest. However, the club is unlikely to take any risks with Dembele by rushing him back into action given his past record with injuries.
Thursday's tests will provide an indicator of where his recovery is and whether he can make it in time for the Real Madrid encounter. Raphinha has stepped up in Dembele's absence, but the Blaugrana does not carry the same threat and venom in attack that they do with the French international.
Barcelona took a major step towards winning the La Liga title with a 2-1 victory over current champions Real Madrid just before the international break. They will now look to move closer to lifting the Copa del Rey trophy should they see off their arch-rivals once more in early April.
The final Clasico of the season will take place at Camp Nou, with Barcelona looking to secure their place in the finals of the competition. Despite the injuries, the Blaugrana will be confident of their chances.
As for Real Madrid, they will be looking to avenge their recent defeat and keep their hopes of silverware alive. The Copa del Rey provides an opportunity for Carlo Ancelotti's side to salvage their season, and they will be desperate to do so at the expense of their bitter rivals.