Although they are setting the early-season pace, Arsenal go into Saturday's game with a number of key players on the sidelines.
United, on the other hand, have had improved under new manager Erik ten Hag since their dismal 4-0 defeat at Brentford and have gone on to win three on the bounce.
Arteta will make a late call on the fitness of Martin Odegaard and goalkeeper Aaron Ramsdale, while Oleksandr Zinchenko could also miss the trip as he has yet to return to training following a knee injury.
"Those two (Odegaard and Ramsdale) they've been assessed. We will see more tomorrow," Arteta said.
"Hopefully they'll be available to train with the team. Unfortunately with Alex (Zinchenko), he's missed two games and still hasn't been able to train with the team yet."
Mohamed Elneny and Thomas Partey are also expected to face lengthy spells on the sidelines of at least weeks, and for the Egyptian, months.
"With Mo it's a little bit easier, we are talking months. With Thomas hopefully we are talking weeks or even shorter than that," the Arsenal manager said.