Thunder Beauty will have a crack at the 1000 Guineas at Newmarket, while Miss Amulet will travel to Longchamp to tackle the French 1000 Guineas (Poule d'Essai des Pouliches).
Thunder Beauty was impressive on her racecourse debut at the Curragh last summer before going on to finish fifth in the Moyglare Stud Stakes at the Curragh and seventh in the Prix Marcel Boussac in Paris.
She will be an outsider for the Qipco 1000 Guineas over the Rowley Mile on May 2, but trainer Ken Condon believes she could outrun her odds.
He said: "Thunder Beauty will go straight for the 1000 Guineas. She seems to be very well and is forward in her coat. Her fast work up to this point has gone very well. She'll take her chance in Newmarket.
"She's relatively lightly-raced. She won her maiden at the Curragh nicely and I thought she ran a lovely race in the Moyglare from an outside draw.
"I'd forgive her France. It was very bad ground and there was a bit of barging and scrimmaging in the straight. Billy (Lee) looked after her when her chance had gone.
"She'll be a big price, but she's by a nice sire and we're happy with her."
Stablemate Miss Amulet won three of her eight starts as a juvenile, including a notable Group Two success over Wednesday's Nell Gwyn Stakes winner Sacred in the Lowther at York.
She rounded off her campaign with two excellent efforts in defeat - finishing second in the Cheveley Park Stakes at Newmarket and third at the Breeders' Cup - and Condon views the French 1000 Guineas as a suitable target.
"Miss Amulet will hopefully start back in the French 1000 Guineas. She'll go straight there on May 16," the trainer added.
"She had a very good year last year and kept progressing. She finished off with a third in the Breeders' Cup over a mile.
"Longchamp might be the most suitable place for her to run in a Classic. In future she may come back in trip.
"Hopefully she has trained on - you never really know until they run.
"She's done well physically, she looks well and is training nicely. All the signs are pretty good. She'll take her chance and we'll make a plan after that."