When: Wednesday, June 9, 01:30 BST
How to watch: Free Sports
Away from the off-the-field controversies, things are going really well for Brazil.
Tite's side have won six straight games and are unbeaten since late 2019. What's more, they're currently top of the World Cup qualifying group with a perfect record to their name.
Paraguay come into this encounter having gone eight games unbeaten. As things stand, Eduardo Berizzo's men are fourth in qualifying and stand a real chance of returning to the World Cup.
Their main problem, however, will be trying to keep at bay a Brazil outfit which has bagged an impressive 14 goals in five games.
Last Three Matches
Brazil 0-0 (4-3p) Paraguay (Copa America - June 28, 2019)
Brazil were taken all the way to a penalty shoot-out when they last met Paraguay in a head-to-head fixture.
The two nations clashed in the quarter-finals of Copa America and it proved to be a close affair with neither side able to score after 120 minutes.
With the score 3-3 in the shoot-out, it was Gabriel Jesus who scored the winner to send Brazil through to the semi-finals.
Brazil 3-0 Paraguay (World Cup Qualifier - March 29, 2017)
In their last World Cup qualifier, it was Brazil who ran riot in a 3-0 victory.
Phillippe Coutinho's 34th minute goal helped the hosts to a lead at half-time.
Then, second-half goals from Neymar and Marcelo sealed a comfortable victory for Brazil.
Paraguay 2-2 Brazil (World Cup Qualifier - March 30, 2016)
A year earlier, Brazil were forced to overturn a two goal deficit when they faced Paraguay away in Asuncion.
Goals from Dario Lezcano and Edgar Benitez gave the hosts a 2-0 lead but with ten minutes remaining, Brazil sprang into life.
Ricardo Oliveira grabbed an 80th minute goal before Dani Alves secured a point with a last-minute equaliser.
Last ten head-to-heads
Paraguay wins: 4
Brazil wins: 4
Paraguay goals: 11
Brazil goals: 15
Brazil's last game of the summer?
South America's premier soccer tournament, Copa America, is set to get underway this weekend.
However, with the competition moved to Brazil, there are growing rumours of possible boycotts - this includes the Brazil national team.
Their discontent stems from the fact that the nation was awarded the tournament despite being the third worst-hit country in the world from the COVID-19 pandemic.
Brazil's players are set to announce a statement following the World Cup qualifier with Paraguay. Should they decide to boycott, this would be their last outing of the summer.
Paraguay - experts in frustration
As mentioned before, Paraguay have enjoyed a lengthy unbeaten run. However, that doesn't necessarily mean that they win many games.
In fact, Paraguay come into this game having only managed one win and five draws from their last six internationals.
Clearly Paraguay know how to frustrate opponents however, that task will certainly be a lot harder against a free flowing side like Brazil.
Gabriel Jesus is yet to get off the mark in this qualifying campaign however, the Man City man is well priced to change that.
At 17/4, the forward offers great value with Betway to score first.