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Can Newcastle stop their slide towards the Championship?
The international break offers every team a chance to reset themselves and, in this case, prepare for the crucial run-in to the season.
Put quite simply, Newcastle needed this break - if they can somehow get back to winning ways, then they have a chance of pulling away from the bottom three against a steadily improving Fulham side.
The Magpies have won just twice in their last 20 matches in all competitions, which is a run to scare any supporter in the Toon Army, after a solid start in the opening months of the season.
Their 3-0 defeat against relegation rivals Brighton & Hove Albion prior to the break will have been a big psychological blow to Steve Bruce's side, but their task won't be any easier against a Tottenham side who are clawing their way towards the top four.
Even more worrying for the Magpies is their lack of potency in front of goal in their barren 20-game run - with just 14 goals to their name in that time.
A win against Spurs would do wonders for Newcastle's confidence, but whether or not that is possible remains to be seen.
Last three Premier League meetings
Tottenham Hotspur 1-1 Newcastle United (September 27, 2020)
The reverse fixture at the Tottenham Hotspur Stadium played out in controversial circumstances, with VAR playing a part in proceedings late in the game.
Despite several excellent saves from Karl Darlow in the Newcastle goal in the early stages, but he couldn't stop Spurs taking the lead after Harry Kane's low ball across goal was turned in by Lucas Moura.
Second-half stoppage time came around with Spurs in front, but Andy Carroll's header in the box came off the arm of an unwitting Eric Dier, giving the Magpies an extremely contentious lifeline. Callum Wilson converted from the spot to earn a share of the points, but it left a bitter taste in Tottenham's mouths.
Newcastle United 1-3 Tottenham Hotspur (July 15, 2020)
After the season restarted last term, Spurs would eventually run out comfortable winners against Newcastle at St James' Park.
A neat team move was well finished by Son Heung-min to open the scoring for Tottenham in the first half, and although Newcastle equalised through an absolute rocket from Matt Ritchie, Harry Kane would quickly put Spurs back in front.
Kane notched again in the 90th minute to put the result beyond doubt, with the England captain scoring his 200th club goal in the process.
Tottenham Hotspur 0-1 Newcastle United (August 25, 2019)
An early-season encounter between Spurs and Newcastle saw the visitors come out on top in this one, with new Magpies signing Joelinton notching his first goal for the club.
Newcastle were on the front foot in the first half, but broke the deadlock after a fine lofted ball from Christian Atsu finding Joelinton in space, who controlled well and rifled past Hugo Lloris into the bottom corner.
Despite Spurs having several big chances towards the end of the game, they couldn't convert them and Newcastle held on to win all three points on the day.
Head-to-head in the Premier League
Newcastle won: 19
Spurs won: 21
Newcastle scored: 75
Spurs scored: 78
Newcastle United 1-2 Tottenham Hotspur
Can Spurs muscle their way into the Champions League places?
If you put Tottenham's disastrous exit from the Europa League at the hands of Dinamo Zagreb aside, their form in the Premier League has gradually improved in recent months.
Jose Mourinho's men are now almost within reach of the top four. With Liverpool's title defence not matching expectations, West Ham's form faltering and Chelsea's shock defeat to West Brom on Saturday, a win for Spurs would see them jump into fourth in the table.
The form book favours Tottenham, too, with five wins out of six in the Premier League seeing Spurs hit their stride in recent weeks.
While banking on a Tottenham win is never a full-on guarantee in the Premier League, they go into Sunday's match as heavy favourites at St James' Park.
Harry Kane has re-found his scoring form in recent weeks, netting in each of his last three games for club and country.
Newcastle have struggled in front of goal with top scorer Callum Wilson having been sidelined since February.