When: Saturday, August 14
Time: 12.30 BST
Where: Old Trafford, Manchester
How to watch: BT Sport 1
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The standout fixture in the opening week of the Premier League. Two teams with rich history and a heated rivalry in Manchester United and Leeds United.
Much of the spotlight has been on the activity of Man United in this summer's window.
Jadon Sancho was the first major signing through the door from Borussia Dortmund for a fee of £73million - a player the club tried to sign prior to 2020/21.
Raphael Varane is the other marquee name to join Ole Gunnar Solskjaer. The Frenchman - who won four Champions League titles and three La Liga titles at Los Blancos - will partner Harry Maguire in the heart of defence.
Add Luke Shaw - arguably England's player of the tournament at Euro 2020 - and Aaron Wan-Bissaka, United perhaps have the best back four in the league. It could prove a vital moment for Ole, who has picked up the reputation as soccer's nearly man.
Three semi-final exits, a Europa League final defeat to Villarreal, and a runners-up spot, there will be pressure on Ole to deliver a trophy at the club this season.
The hosts are possibly the best prepared for a season since the good old times with Fergie once all of their players are available for selection. But they must have their whits about them because Leeds United mean business.
One of the fittest teams in England, Leeds' attacking philosophy won over neutrals last season and they'll be confident of improving further in 2021/22 following the additions of Junior Firpo, Lewis Bate and the permanent deal of Jack Harrison.
Last three results:
April 25, 2021: Leeds United 0-0 Man United
Leeds United continued their impressive record against top teams in 2020/21 by holding Man United to a goalless draw at Elland Road.
While it was an impressive point earned, Leeds only produced six shots on target making it the joint-fewest in a league game under Marcelo Bielsa - the other being against Burnley in July 2020.
December 20, 2020: Man United 6-2 Leeds United
What a game. Scott McTominay scored twice in the first three minutes to set the pace at Old Trafford before Bruno Fernandes and Victor Lindelof made it 4-1 by half-time.
Fernandes scored a second from the penalty spot and Daniel James - a player previously linked with a move to Leeds - scored their sixth.
Liam Cooper and Stuart Dallas were on the scoresheet for the Whites. The victory ensured Man United kept their unbeaten record against Leeds at Old Trafford in their last 13 meetings, winning nine of them.
September 20, 2011: Leeds United 0-3 Man United
Michael Owen bagged a brace as Man United advanced into the fourth round of the League Cup. Ryan Giggs scored the third goal just before the end of the first-half.
The game also saw Paul Pogba make his senior debut for the club in his first spell under Sir Alex Ferguson.
Last ten head-to-head games
Man United wins: 6
Leeds United wins: 2
Man United goals: 20
Leeds United goals: 11
Phillips to be carded
Kalvin Phillips' stock is at an all-time high following his displays for England during the summer. He is the glue that keeps Leeds together in the middle and being a local lad, he'll be fired up against Man United.
In 61 yellow cards Leeds received in 2020/21, Phillips was put in the book 10 times and in their 6-2 defeat to Man United in December 2020, he was carded.
For the England ace to be given a card, it is 7/4.
Can Leeds end a winless record?
Leeds United are yet to record a victory over the Red Devils in 16 top-flight fixtures - the last being in February 1981. If the visitors don't walk away with three points then they will equal their longest winless run on the road in the top division against a team.
Yes, Man United have strengthened in defence, but Raphael Varane will not be in the matchday squad for Solskjaer. Victor Lindelof is likely to start in his place while Jadon Sancho will make his debut.
They also have Marcus Rashford out who is recovering from shoulder surgery. It means Anthony Martial will spearhead the attack for United. Leeds conceded 54 goals last season - the most from a team that finished in the top-half - and gave away 10 penalties.
Only Man City (11) and West Bromwich Albion (12) made more fouls inside the 12-yard box. Bruno will be licking his lips…
While their most recent encounter ended in a stalemate, make no mistake about it both teams will be desperate to impress in front of fans.
For Leeds to get a hold of the game they will want to score early and create a hostile atmosphere for a Man United side under pressure to deliver silverware this season.
Patrick Bamford had an impressive 2020/21 campaign, notching up 17 goals in 38 appearances. He has proved he is a man for the big occasion and he'll fancy his chances against Lindelof in particular.
Last season, Bamford scored the opening goal for Leeds on seven occasions, and you can back him here at 13/2 to score first.