When: Tuesday, May 18, 18:00 GMT
How to watch: Sky Sports
Building up to the final
All eyes will be on Man United to see if they can get over the line and secure second position in the league table, after last week's loss to rivals Liverpool.
Already-relegated Fulham provide the opposition for The Red Devils and a home win is certainly expected by most.
Three points would move United onto 73 points, making it mathematically impossible for third-placed Leicester to catch them.
Perhaps more importantly, Solskjaer's players are aiming to go into the Europa League final against Villarreal, on the back of good form and to prepare in the best possible manner.
Their European opponents warmed up for the game with the thrashing of Europa League regulars Sevilla, coming away 4-0 victors including a hat-trick for Carlos Bacca. They also have a vital final league match against Real Madrid; one they cannot afford to lose if they want to secure a top six finish and European football next season.
Last three Premier League meetings:
Fulham 1-2 Man Utd (January 20, 2021)
Victory helped The Red Devils climb back to top spot in the table thanks to a wonderful Paul Pogba strike to win the match in the second half.
Fulham took advantage of a flimsy offside trap, as Ademola Lookman latched onto an aerial through ball to calmly slot past the goalkeeper.
Alphonse Areola could not keep a grip of Bruno Fernandes' cross and Edinson Cavani pounced to bring the scores level.
It was Frenchman Pogba, though, who grabbed the headlines, making Fulham pay by not closing him down and unleashing a left-footed strike from more than 25 yards out. Areola had no chance of saving the shot and United left London top of the table.
Fulham 0-3 Man Utd (February 9, 2019)
Paul Pogba once again stole the show, scoring twice to put his side firmly in Champions League qualification contention.
Anthony Martial also had a game to remember, setting up Pogba for his first on 14 minutes and then scoring a magnificent solo goal to give United a comfortable lead.
Pogba's penalty on 65 minutes handed Man United victory with Fulham failing to create any chances of note and the loss left them seven points from safety.
Man Utd 4-1 Fulham (December 8, 2018)
Man Utd secured their first win in five games and Romelu Lukaku ended a 997 minute goal drought in all competitions.
Goals from Ashley Young, Juan Mata, and Lukaku put the home team out of sight before the interval.
Aboubakar Kamara, who came off the bench, won and converted a penalty but Fulham shortly after were reduced to ten men when Andre-Frank Zambo Anguissa received a second yellow card.
Marcus Rashford powerfully added a fourth and confirmed a much-needed win for Man United at Old Trafford.
Premier League head-to-head
Man Utd wins: 21
Fulham wins: 3
Man Utd goals: 67
Fulham goals: 30
Will Fulham stick by Scott Parker?
It's fair to say that Fulham have struggled with the demands in the Premier League, however their effort and commitment cannot be denied. A large part of that is down to the leadership of manager Scott Parker, who has undoubtedly done everything he can to keep Fulham in the top-flight.
As relegation beckons, it is expected that The Cottagers will stick with the man who got them promoted to the Premier League in 2019/20.
Parker has shown top qualities in his short managerial career and is touted to go on and do bigger and better things in the future. The former England international is currently third-favourite to become Tottenham's next manager, which shows how highly thought of he is.
Scott Parker is a best priced 9/1 to be the next Tottenham manager (Paddy Power), but is as short as 4/1 with most other bookmakers.
Scoreline prediction: Man Utd 3-1 Fulham
United's record against Fulham speaks volumes: unbeaten in the last 13 meetings between the two sides. The only slight concern is that Solskjaer's team have lost their last two league games, 2-1 at the hands of Leicester and 4-2 against Liverpool.
Fulham, though, are a completely different proposition and they slumped to yet another defeat at the weekend against a team in similarly poor form, in the shape of Southampton.
Manchester United will have had time to recover from their four games and eight days and with no game the past weekend, should be refreshed and ready to hit the ground running. 10,000 fans could be at Old Trafford and that could boost the spirits in the United camp too.
Mason Greenwood missed out on a starting place against Liverpool, but it would be no shock to see him start on Tuesday evening.
Paul Pogba has flourished in his last two appearances against The Cottagers, netting three times in two games against them. If Pogba starts the game, it would be a shrewd decision to back him to score first.
The midfielder is 10/1 to score first with the majority of bookmakers.