When: Sunday, May 16, 19:00 BST
How to watch: BT Sport
Qualifying for next season's Europa League would bank Everton a nice bonus of $3.5million.
In the world of football, amounts like that are nothing more than pocket change. Instead, the true motivation for the Merseyside outfit is to return to a European competition for the first time since the 2017/18 season.
Realising their European dream won't be an easy feat though. Carlo Ancelotti's men are currently eighth in the standings and sit three points away from the Europa League places.
With Arsenal, Tottenham and West Ham still battling for the same prize, Everton will need to pick up maximum points against Sheffield United if they are to become serious challengers for the top six finish.
Last Three Matches
Sheffield United 0-1 Everton (Premier League - December 26, 2020)
There was no Christmas miracle for the Blades when they hosted Everton towards the end of the calendar year.
Both teams had a fair few goal attempts but neither side was able to take the initiative for a majority of this encounter.
Then, in the 80th minute, Gylfi Sigurdsson stepped up to the plate and bagged the winning goal to seal all three points for the Toffees.
Sheffield United 0-1 Everton (Premier League - July 20, 2020)
When the two sides met towards the end of the previous season, viewers were treated to another close encounter.
After a cagey opening half, Everton finally found a breakthrough when Richarlison bagged a goal in the 46th minute.
Sheffield failed to find the equaliser as the Toffees took all three points back to Merseyside.
Everton 0-2 Sheffield United (Premier League - September 21, 2019)
Sheffield United picked up their first win over Everton in 26 years when they met at Goodison Park back in 2019.
Blades took the lead in the 40th minute courtesy of an own goal from Yerry Mina. Everton looked for an equaliser but were denied by a well organised Sheffield outfit.
In the 80th minute, the visitors extended their lead through Lys Mousset. Chris Wilder's side held on for the win and took all three points back to South Yorkshire.
Last ten head-to-heads
Everton wins: 5
Sheffield United wins: 3
Everton goals: 12
Sheffield United goals: 9
Everton's final push for Europe
With three games remaining, the pressure is on for Everton to bank a top six finish.
After their meeting with Sheffield United, the Toffees then take on Wolves at home and Man City at the Etihad.
Ideally, Carlo Ancelotti would like to see his men pick up all nine points on offer. However, with teams around dropping points - specifically West Ham and Tottenham - there may be a glimmer of hope even if the Toffees fail to win all three games.
Nevertheless, looking at Everton's available squad, they certainly have the necessary tools to get the better of this already relegated Sheffield United side.
The white flag was out months ago
Sheffield were out for the count months ago. With a measly 17 points to their name, this has been a woeful season for the South Yorkshire outfit.
Recent results have been especially bad. Paul Heckingbottom's side have lost eight of their last nine competitive games. A sole win over Brighton in April helped to momentarily break the mould.
Scoring goals has been a particularly evident problem for the Blades. The team have scored one goal in five games; conceding ten in the same space of time.
Dominic Calvert-Lewin is the man to watch from a goalscoring perspective. The England international has scored two first-half goals in his last three Premier League appearances.
The Everton frontman is currently well priced at 10/3 to open the scoring in this contest.