The Citizens have taken a firm grip on the Premier League, sitting pretty at the top of the table by a hefty margin.
Manchester City and Arsenal have been going head-to-head since as early as 1893, and have met 202 times overall.
The Sky Blues have won just 59 of those encounters, with the side from north London registering 98 victories. 45 games have ended in a stalemate.
Although, Sunday's visitors to the Emirates Stadium have lost just once in their last 10 meetings between the two sides.
Sterling will be looking to maintain that fine run of results this weekend.
Let's have a look at the numbers that matter.
Sterling has played against Arsenal on 17 occasions in his career; he has bagged seven goals and assisted three times.
The England international has been part of a winning team eight times, and has lost the Gunners three times.
The two teams last met in the EFL Cup in December, with City running out 1-4 winners.
Sterling has notched eight goals so far this season, and he'll be striving to add to that tally on Sunday.
Manchester City 1-0 Arsenal
17 October 2020
This game was the first game back from an international break, and City had drawn with Leeds United in their previous outing, so this was an important win for Guardiola's side.
The hosts opened the scoring after 23 minutes, when Sterling was on hand to slide the ball into an empty net after Phil Foden's initial shot was well-saved by Arsenal 'keeper Bernd Leno.
Despite the relatively narrow scoreline, this was a game in which the Etihad outfit controlled for the vast majority of proceedings. Foden and Riyad Mahrez forced smart saves from Leno.
Bukayo Saka had Arsenal's best chance of the match, going one-on-one with Ederson, but the Brazilian 'keeper made himself big and made an important stop.
City continue to march towards reclaiming their title from the hands of Liverpool.
Manchester City 3-0 Arsenal
17 June 2020
Project Restart saw Premier League football return after it had been suspended due to COVID-19.
The six-time champions of England returned and sparkled against the Gunners.
A David Luiz blunder allowed Sterling to ghost in and smash home inside the six-yard box.
Luiz's night went from bad to worse in the early stages of the second half, when he dragged Mahrez down in the penalty area. Anthony Taylor pointed to the spot and sent the Brazilian defender for an early bath.
De Bruyne dispatched the spot-kick, sending Leno the wrong way.
Foden applied the gloss onto the scoreline in injury time, when he fired home after Sergio Aguero's effort rebounded off the post.
Liverpool would go on to win the Premier League, with City finishing in second.
Arsenal 0-3 Manchester City
15 December 2019
The return fixture to the previous game we looked at.
City had this one wrapped up early on, with all three goals coming in the first half.
De Bruyne gave the visitors the lead within the first two minutes, with a thunderous strike from just inside the penalty area.
Their lead was doubled soon after when De Bruyne put the ball on a plate for Sterling to tap home his low cross.
The Belgian netted his second just before half-time with a crisp, low finish from just outside the penalty area.
The blue side of Manchester could've added to their tally, with De Bruyne hitting the woodwork and Gabriel Jesus was denied by Leno.
Tip for the fixture
With Pep Guardiola's side continuing their winning run and Arsenal putting four past Leeds in their last match, Manchester City to win and both teams to score can be found at 9/4 with Paddy Power (price correct at the time of writing, subject to change).