The Blues have confirmed their intentions of winning this season's Premier League with the marquee signing of Romelu Lukaku.
When, where and how to watch
When: Saturday, September 11, 5.30pm BST
Where: Stamford Bridge
How to watch: Sky Sports
(All text odds are correct at time of publication and are subject to change)
Lukaku wasted no time on his homecoming, netting on his debut against London rivals Arsenal. With two wins from three, Thomas Tuchel's most impressive result was actually a draw against Liverpool.
Playing with 10 men for the whole of the second half, Chelsea ensured they maintained their unbeaten start to the season at Anfield.
Deadline day signing Saul Niguez will be available for selection and is in-line to make his debut in the fixture. For Dean Smith's Villa, it has been a tough start.
A poor performance on the opening day of the season saw them taste defeat to Watford although they bounced back with a less than convincing win over Newcastle. Newbie Danny Ings - who cost Villa £25million - scored a spectacular overhead kick to seal three points.
A draw to Brentford leaves them with four points from a possible nine. However, Villa have yet to field their strongest side. Ollie Watkins missed the first game through injury and the club were dealt a blow before facing Newcastle with new signing Leon Bailey picking up a knock.
The good news is, Bailey and Watkins are available. The bad news, they will be without Emiliano Martinez and record signing Emiliano Buendia who are both being forced to quarantine.
Last three meetings
Aston Villa 2-1 Chelsea (Premier League - May 23, 2021)
On the final day of the 2020/21 season, Chelsea travelled to Villa Park needing a win to guarantee a top four spot.
Thomas Tuchel was juggling with Champions League qualification and also an all-English final against Manchester City days later in Europe's biggest competition.
Fans returning to stadiums gave Villa extra motivation and goals from ex-Chelsea star Bertrand Traore and Anwar El Ghazi's penalty guided the Midlands side to victory.
Chelsea still managed to finish fourth and went on to win the Champions League, defeating Man City 1-0.
Chelsea 1-1 Aston Villa (Premier League - December 28, 2020)
Chelsea went into the game having lost three of their last four fixtures but started brightly and were soon in the lead thanks to an Oliver Giroud header.
However, their lead was short-lived with Anwar El Ghazi cancelling out the Frenchman's goal with the winger converting Matty Cash's cross.
It was the Dutchman's fifth goal in as many games and it saw Villa move up to fifth position in the league, one place above Frank Lampard's Chelsea.
Aston Villa 1-2 Chelsea (Premier League - June 21, 2020)
Christian Pulisic inspired a second half Chelsea comeback to seal victory at Villa Park,
The home side took the lead after Kepa failed to keep hold of Anwar El Ghazi's shot and Kortney Hause was there for a tap in.
Pulisic came on as a substitute in the 55th minute and changed the game on its head, drilling the ball into the top corner before an Oliver Giroud deflected goal from 15 yards earned all three points.
Last 10 head-to-heads
Chelsea wins: 7
Aston Villa wins: 2
Chelsea goals: 19
Aston Villa goals: 8
Can Aston Villa spoil the party?
Villa's victory over Chelsea on the final day of last season was their first win over Chelsea since 2014.
However, Thomas Tuchel's side look like they mean business this season and their main objective is to win the league.
In the middle of the park, they have Jorginho, Kane and new signing Saul Niguez - not too shabby is it?
Tuchel is sweating on the fitness of trio Romelu Lukaku, Kai Havertz and Christian Pulisic though.
Meanwhile, Villa are continuing life without Jack Grealish and you can now see why they placed a £100million release clause in his contract.
But with Leon Bailey set to return to the fold and Ollie Watkins in contention to start with Danny Ings, they will be looking to take the game to Chelsea.
Dean Smith's new look side have not started as quick as last season and against a Chelsea side brimming with confidence, nothing suggests anything other than a home win.
Anwar El Ghazi enjoys playing against Chelsea having scored against them in the two most recent matchups.
The winger has become an integral part of the side and notched up 11 Premier League goals last season.
El Ghazi has bagged three goals in all competitions this season so far and should Villa win a penalty he'll get the nod over Danny Ings.
Both teams to score
Villa may not be in full flow yet but they have scored in every game so far but Danny Ings is proving to be a hit, scoring twice in three games.
In contrast, Chelsea have scored six goals by six different players while also keeping two clean sheets in three.
Both teams have scored in their previous four meetings with three of them ending in 2-1 results.
McGinn to be carded
The Scot loves a foul. In 67 Premier League appearances, John McGinn has made 81 fouls and seen the book on 15 occasions although he is yet to see red.
As the game goes on, Villa will tire and the middle of the park will open up.
With the likes of Jorginho, N'Golo Kante, Saul Niguez and Mason Mount playing for Chelsea, Villa are likely to be under the cosh.
McGinn just won't be able to resist lunging in, especially if his team are under pressure in the final 20 minutes of the fixture.