Borussia Dortmund are one of the teams in action and they could have their hands full when they welcome high scoring Hoffenheim to the Signal Iduna Park.
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Burton vs Cheltenham
Burton's three match winning run came to an end last weekend in pretty comprehensive style.
Albion were thrashed 3-0 by Cambridge United as their perfect record crumbled in what was a calamitous second-half.
Cheltenham meanwhile have only recorded one win from their opening four games. Michael Duff's side have no problem scoring goals - having bagged six so far - but defensively the Robins have been woeful, conceding eight times.
With both teams scoring and conceding on a consistent basis, the over 2.5 goals bet is the way to go.
Rochdale vs Colchester
Friday's League Two action will see Rochdale host Colchester at the Spotland stadium.
One thing which this fixture has consistently provided is goals with 15 efforts scored over the last four games.
Our recommendation though, is to back the both teams to score market. This is a bet that has landed in five of the last six head-to-heads and one which has landed every time this fixture has been played in Rochdale.
Nantes vs Lyon
Lyon have started the season with a bit of a stinker having claimed just two points form their opening three games.
This Friday they travel away to Nantes who are looking to bounce back from their 1-0 loss to Rennes.
Early signs point to serious defensive vulnerabilities at Lyon. The club have conceded seven goals this season, an amount only topped by defending champions Lille.
With that in mind, we're backing the both teams to score bet - a market that has proved successful in four of the last six head-to-heads between these sides.
Borussia Dortmund vs Hoffenheim
Hoffenheim have been Borussia Dortmund's bogey team for the last three years and that run could very well continue this season too.
Marco Rose's men have only recorded one win over Die Kraichgauer in seven attempts. What's more, BVB will come into this game on the back of a 2-1 loss to Freiburg.
Hoffenheim meanwhile, are currently second in the table following their 4-0 demolition of Augsburg and an entertaining 2-2 draw with Union Berlin.
This also promises to be an entertaining contest which is why our tip is to back the over 3.5 goals bet - a market which has proved successful in four of the last seven encounters.
Dynamo Moscow vs Lokomotiv Moscow
The two best placed Moscow clubs will go head-to-head this Friday night as Dynamo host Lokomotiv at the VTB Arena.
Dynamo, who are currently third in the standings, have won four of their opening five games this season.
Lokomotiv, on the other hand, are yet to be beaten having claimed 11 points from their five league encounters.
There's little to separate both clubs in recent head-to-heads with both clubs managing two wins form their last five meetings.
With that in mind, we're backing the draw.
Valencia vs Alaves
Valencia will be looking to maintain their unbeaten start to the season when they take on Alaves.
In recent years this has been a closely fought fixture with the last three meetings all ending in draws.
Alaves didn't get off to the best of starts having lost 4-1 to Real Madrid and 1-0 to Mallorca. With that in mind, we're favouring Valencia in the outright market.
The Bats have won this fixture seven of the last eight times when it has been played at the Estadio de Mestalla. Now that's a run we can get behind.