Tottenham welcome Aston Villa looking for redemption after three brutal defeats to Crystal Palace, Chelsea and north London rivals Arsenal.
The last time these two sides met at the Tottenham Hotspur Stadium, Ollie Watkins scored a crucial winner to give Villa the three points.
However, in their seven previous meetings, Spurs have won six and Nuno Espirito Santo will be hoping that rich vein of form continues to ease the pressure on his shoulders.
When, where and how to watch
When: Sunday, October 3, 2pm BST
Where: Tottenham Hotspur Stadium
Spurs need to turn the tide
Nuno Espirito Santo has a job on his hands having seen his side concede three goals in each, But at least Harry Kane brought an end to his lean spell with a hat-trick in the 5-1 midweek over NS Mura in the Europa Conference League. Maybe things are looking up for the England captain.
In contrast, Aston Villa earned an impressive victory at Old Trafford, defeating Manchester United 1-0 thanks to a Kortney Hause goal. The biggest storyline, however, was Bruno Fernandes' penalty, which he blazed over in stoppage time and subsequent social media apology.
Villa, meanwhile, have now recorded two wins on the bounce and look a force to be reckoned with.
(All text odds are correct at the time of publication, but the ones in the pretty blue boxes are bang up-to-date)
Three victories, including an opening-day win over Premier League champions Manchester City, saw Spurs top the table coming into September and Nuno named Manager of the Month.
However, a shock 3-0 defeat to Crystal Palace followed by back-to-back losses to London rivals Chelsea and Arsenal have put Nuno under scrutiny.
Spurs need a strong performance on Sunday, otherwise it could see Daniel Levy handing out a P45 in October. Make no mistake about it, they're up against it with Dean Smith's Villa looking like they have overcome their Jack Grealish hangover.
The formation change to 3-5-2 has seen John McGinn flourish in midfield, while Matty Cash is producing sensational performances as a wingback.
Cash - linked with a Poland call-up due to his Polish mother - scored his first goal for the club against Everton two games ago and it was a beauty.
Last three meetings
Tottenham 1-2 Aston Villa (May 19, 2021)
In front of 10,000 fans at the Tottenham Hotspur Stadium, Steven Bergwijn's thumping strike handed Tottenham the lead in the eighth minute.
Villa's response deserved an equaliser and it was Spurs left-back Sergio Reguilon who got Villa level after he sliced Nakamba's cross into the top corner.
Arsenal fan Ollie Watkins all but ended Spurs' hopes of qualifying for the Europa League as Villa went on to win 2-1.
Aston Villa 0-2 Tottenham (March 21, 2021)
Jose Mourinho's Tottenham rebounded from their Europa League humiliation against Dinamo Zagreb to earn an away win at Villa Park.
Carlos Vinicius netted the opener before Harry Kane's second-half spot-kick ensured Tottenham remained in the hunt for the Champions League.
The defeat left Villa in 10th place and any hopes of qualifying for Europe all but ended.
Aston Villa 2-3 Tottenham (February 16, 2020)
A sensational game at Villa Park saw Tottenham earn a dramatic win. Villa made the quicker start and took the lead thanks to a Toby Alderweireld own goal - with the Spurs defender nodding in Anwar El Ghazi's cross.
Alderweireld corrected his mistake with the equaliser, rocketing a shot into the right-hand corner of Villa's net from an acute angle.
Heung-min Son and Bjorn Engels scored for Spurs and Villa, respectively, to make it 2-2. Son then earned all three points for Tottenham, reacting to an Engels error to score the winner in the 94th minute.
Tottenham wins: 75
Aston Villa wins: 57
Ings to deliver
Danny Ings has only scored two goals from six appearances in the league this season but his stats do not reflect his performances.
He has also made two assists, the most recent of which was a superb ball to Leon Bailey in the 3-0 drubbing of Everton.
In his last game against Spurs, for Southampton, Ings was on target in a 3-2 FA Cup fourth round defeat. And facing a leaky defence, he will be fancying himself to follow up.
Elsewhere, Harry Kane has yet to open his account domestically but in Europe he is now flying. Villa have a solid defence but Tyrone Mings is prone to making at least one mistake a game.
Should he produce an error like the one against Chelsea which handed Romelu Lukaku a goal then Kane is sure to capitalise.