Our search for the very best bets has taken us to four different competitions in three countries on Tuesday, with six selections from the Carabao Cup, Serie A, La Liga and League One.
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Arsenal vs Leeds
Mikel Arteta - who was previously favourite to leave his post after three heavy defeats at the start of the season - is enjoying his most successful run this season.
Arsenal are undefeated in seven games across all competitions since their 5-0 drubbing to Manchester City.
A cup run for the Whites meanwhile would be a welcomed distraction from their current form in the league.
The Yorkshire club have managed just one win from nine in the Premier League and scraped past Fulham in the third round of the competition, winning 6-5 in a penalty shootout.
Based on recent results from both sides, we're going for an Arsenal win and both teams to score.
Chelsea vs Southampton
Thomas Tuchel will be eyeing up the Carabao Cup as another trophy he can add to his cabinet as Blues boss.
The German coach will be without striking duo Romelu Lukaku and Timo Werner, who are both ruled out of the cup clash because of injury. If they are being missed, Chelsea certainly didn't show it in their previous outing, thumping strugglers Norwich City 7-0 in the Premier League.
Mason Mount bagged a hat-trick while Ben Chilwell, Reece James and Callum Hudson-Odoi also chipped in.
Southampton have reached the fourth round of this tournament for the third time in four years but only edged out Sheffield United on penalties in the previous round.
Despite an 8-0 win over Northampton in the second round, goals have been hard to come by for Ralph Hasenhuttl's side since the departure of Danny Ings.
Southampton beat Chelsea just once in 13 meetings and based on current form and recent history, we expect the European Champions to not only progress but to also score over 2.5 goals.
AC Milan vs Torino
Stefano Pioli has found a winning formula at Milan, even if they struggle to keep a clean sheet.
They have won eight of nine games domestically, the only game being against Juventus in which they have dropped points.
Olivier Giroud has scored three in five and netted in their most recent win over Verona - a match that saw them produce a sensational comeback to win 3-2.
Torino have had a topsy-turvy season and are winless from four, although their last two games have been defeats to Juve and high-flyers Napoli.
Based on the way they have started this season, we're backing title challengers AC Milan to deliver once again.
Villarreal vs Cadiz
Both teams are in search of a win after consecutive defeats in the league. Villarreal - under Unai Emery - currently sit in the bottom half on the table, just four positions above the opposition who sit in 17th.
Villarreal have drawn five of nine games, four of them ending 0-0. Cadiz have also struggled to find the net - recording the same scoreline on two occasions and managing to score just seven goals from their opening nine games.
The sides have met four times prior to this La Liga clash and Cadiz are yet to earn a win over Villarreal, with three defeats and a draw - the most recent being a 2-1 victory for Emery's men in March.
This fixture may not be one for the neutrals but based on what Villarreal can do - which is win games by four goals, something they have done twice this season - we are backing them to find their scoring boots and win with a -1 handicap.
Espanyol vs Athletic Bilbao
The visitors have enjoyed a solid start to the La Liga season, losing just once in nine games. They're not exactly the league's high scorers having bagged just nine goals, but then again they are solid at the back having conceded five in return.
They have a system in place which is to make them hard to beat and so far, everything has gone according to plan for Marcelino Garcia Toral's side.
Espanyol currently sit in 11th position but have played one more game than Bilbao, who are in eighth place.
With three wins from five though, the hosts are in good form. What's more, one of those victories came against Real Madrid.
This should be a tight affair and we are backing a draw with both teams to score.
Doncaster Rovers vs Cambridge United
This time last season Doncaster were bidding for promotion - it's mad how much can change in such a short time.
Richie Wellens, former Salford City manager, has a job on his hands with a limited budget and no senior striker - something the Doncaster fans have complained about.
Rovers are sitting second from bottom but did pick up a win in their last game, overcoming Cheltenham 3-2; although they were 3-0 up at one stage.
The meeting could not come at a better time for Doncaster with Cambridge winless from six in the league.
Both have shipped in 23 goals from recent games but when it comes to scoring, Cambridge have double the amount with 18 compared to Doncaster's nine.
They are facing each other for the first time since 2017 - a game which ended 3-2 to Doncaster in League 2. Sadly, with Rovers struggling to find the net and Cambridge out of form, we don't expect a five-goal thriller here.