The Polish international completed his blockbuster move to Barcelona two weeks ago after the Spanish giants agreed a £40million transfer fee, but is yet to score in three friendly starts.
Several of Barcelona's best efforts against New York fell to Lewandowski, who looked lively during the match but was unable to capitalise on several gilt-edged chances that fell to him, either hitting them straight at the home side's keepers or putting them over the bar.
Ousmane Dembele scored the opening goal in the 40th minute for Barcelona, with Memphis Depay taking advantage of a defensive miscommunication to seal the victory in the dying moments of the game.
That Dembele's third goal in this US tour, is one more than the two he scored in 32 appearances for Barcelona last season.
Lewandowski's first attempt at goal came in the 17th minute, a header which he put over the crossbar. Three minutes later he blasted another shot over the bar. Keeper Carlos Coronel denied the Polish international again in the 24th and 30th minute.
Even Lewandowski started to see the funny side, a wry smile creeping across his face after substitute keeper Ryan Meara flicked another one of his powerful shots over the bar in the 58th minute.
Lewandowski was eventually replaced by Depay in the 72nd minute.
Barcelona now head back to to Spain with three wins and a draw from their US tour, with their final friendly against Mexican side Pumas UNAM at Camp Nou on Sunday, August 7.
Lewandowski is expected to make his competitive debut for Barcelona against Rayo Vallecano when the club's La Liga campaign gets underway on August 13.