Nuno Espirito Santo's dream start to life as Tottenham manager has quickly soured and the Portuguese manager now finds himself second favourite in the Next Premier League Manager to Leave market.
Spurs sat atop the Premier League at the close of August having won their first three fixtures. However, they have subsequently lost their next three games, with Sunday's 3-1 defeat at the hands of north London rivals Arsenal leaving them down in 11th.
A lack of goals is partly to blame for the wheels coming off, with Heung-min Son's consolation at the weekend only their fourth goal this season and first in their last three.
Star striker Harry Kane has yet to score or assist in the Premier League since a summer of speculation linking him with a move to Manchester City, while at the other end, Spurs have conceded nine in their last three.
It all adds up to odds of just 4/1 on Santo being the next top-flight manager to leave his post.
"While three successive defeats shouldn't necessarily sound the alarm bells, the manner of the losses and his ability to get the best out of Harry Kane is the most troubling factor," said Grenham.
"It appears certain sections of the Tottenham support have already lost faith in their new boss, with #nunoout trending on social media.
"With an international break coming up, he really needs a result against Aston Villa on Saturday."
The big winner from Sunday was opposite number Mikel Arteta who is now 6/1 with Planet Sport Bet to be the next managerial departure.
Arteta had been as short as 4/9 following a nightmare opening to the campaign which saw the Gunners lose their first three Premier League matches without scoring.
Arteta has also seen the odds on his Arsenal side to finish inside the top four half from 12/1 to 6s.
Bruce is 2/1 to be the next Premier League manager to leave.