Expectations at the start of the campaign were high at Old Trafford following summer signings of Cristiano Ronaldo, Jadon Sancho and Raphael Varane.
However, instead of competing with the league's best, United endured a wretched start, which culminated with the sacking of Ole Gunnar Solskjaer.
Ralph Rangnick filled the role on an interim basis, but the highly-rated German failed to inspire a top four bid, despite numerous opportunities to overtake Champions League-chasing rivals Arsenal and Tottenham.
The Red Devils head into their last game of the season knowing they need a victory in order to secure a place in the Europa League and avoid slipping into the third-tier European competition, the Europa Conference League.
As well as their final placing, United will also be playing for pride according to goalkeeper David de Gea.
The Spaniard said: "We know (this season has) been difficult. But at least just for (the fans) and for our pride (we will) try to win the game.
"(I want to) at least give a win for the fans because they have been absolutely amazing for the whole season and it's great to have them at every single game."
Despite the team's underwhelming campaign, De Gea is pleased with his contributions.
The Spaniard won the club's Player of the Year award a record four-times, and is currently the favourite to win in once again.
He said: "It will always have been a tough season for us, but I am very proud of my season, to be honest.
"I worked really hard in the summer to be here and be ready to play and show my qualities for the team.
"I think I did very well. I played very consistent this season and helped the team a lot."