After a goalless draw in the first FA Cup first round meeting between these two sides, they head to the Sportnation.Bet Stadium to do it all over again.
The initial fixture was the first time the pair have ever met in a competitive game, which is understandable given Solihull Moors were only founded in 2007.
In their respective leagues, however, the two are both enjoying rather successful seasons. Leam Richardson's Latics sitting second in League One, while Neal Ardley's Moors are eighth in the National League.
With their replay set to be broadcast across the nation on Tuesday evening, Planet Sport brings you all you need to know ahead of the big game.
When, where and how to watch
When: Tuesday, November 16, 19.45 BST
Where: Sportnation.Bet Stadium, Solihull
How to watch: ITV4
Best bets for Solihull Moors vs Wigan
Charlie Wyke to score anytime
Last time out
Wigan Athletic 0-0 Solihull Moors (November 6, 2021)
Despite the 52 league places between the two sides at kick-off, Solihull admirably held League One leaders Wigan to a goalless draw at the DW Stadium.
Goalkeeper Ryan Boot was the hero for the visitors, who were under pressure for much of the encounter, as he made several impressive saves from Gwion Edwards.
Moors were not without their chances, though, as Jamey Osborne saw a header pushed onto the crossbar by home stopper Jamie Jones.
However, neither side was able to break the deadlock within normal time, sending them both back to Solihull for round two.
Recent cup form
Despite being crowned shock champions in 2013, Wigan have endured a dire recent run in the FA Cup, and their run to the quarter-finals in 2017/18 has been followed by exits at the first hurdle in every year since.
The nadir of that winless run, which now stands at five matches, was an ignominious 3-2 defeat at home to National League North outfit Chorley last season.
Solihull, meanwhile, are the opposite, and are bidding to reach the second round proper for the fourth successive season, and fifth time in six years.
That is the furthest they have ever gone in the FA Cup, but they have knocked out EFL sides on several occasions, with the most notable scalps being those of then-League Two sides Scunthorpe United and Yeovil Town.
Both sides flying high
Solihull come into this clash on the back of a chastening defeat at Notts County in which they were roundly played off the park in front of a record non-league crowd of 12,843, but they remain firmly in the play-off race.
Heading into that trip to Meadow Lane, they were unbeaten in eight games, and have built much of their success on a strong defence that conceded just one goal throughout the whole of October.
They are currently eighth in the fifth tier, just outside the play-off spots on goal difference.
Richardson's Latics are enjoying even more of a successful season, and are only two points behind League One leaders Plymouth Argyle with a game in hand.
They have established themselves as something of a yo-yo team between the second and third tiers recently, and are chasing a third promotion to the Championship in seven seasons.
It is a similar tale for them in terms of their defence, too, with the 13 goals they have conceded this term meaning they possess the second-best defence in the division.
Their form of late has been a touch mixed, but they are currently on a four-match unbeaten run in all competitions.
Goalscorer bets for Solihull Moors vs Wigan
Neither the Moors nor the Latics are blessed with a free-scoring attack, instead basing their respective league successes around rock-solid defences.
However, that is not to say both sides don't have any striking talent at their disposal; quite the opposite in fact, with both perfectly capable of finding their opponents' net while successfully defending their own.
For Wigan, look to Will Keane for the goals. The former Manchester United forward has scored seven and assisted four more this season, putting him at the top of the club's charts for the former, and second for the latter.
He would be an easy one to plump for in your prediction to find the net, but there is another tasty option in Charlie Wyke, who was the only player from either side to have the ball in the net in the original tie.
He was denied in that instance by the offside flag, but if he can iron out that particular crease, he has already proved he knows how to beat this Solihull defence.
For Tuesday's hosts, their goalscoring exploits are quite a lot more limited, but they do have a very obvious choice when it comes to picking a man to find the net.
Attacking midfielder Joe Sbarra is their top scorer this term with eight, including two against much-fancied Wrexham earlier in the year, and he is equally adept with either foot.
Outrights for Solihull Moors vs Wigan
The winner of this tie will face a trip to Colchester United and will be able to start dreaming about being in the hat for the third round and the arrival of the big boys.
With that in mind, it will be a battle and goals may be at a premium again. But given their dominance in the first leg, I'd be surprised if the superior fitness and quality of Wigan don't see them through. However, it may need more than 90 minutes to split them.