Constitution Hill's tilt at the Unibet Tolworth Novices' Hurdle will go without Nicky Henderson in attendance as the legendary jumps trainer is currently self isolating with Covid-19.
Henderson told his Unibet blog he "feels fine" and isn't unwell, but the 71-year-old admitted he will find it hard watching on TV as one of the most exciting horses in his yard has his toughest test to date.
"I'm afraid I am under lock and key and self isolating at home at Seven Barrows after catching the dreaded Covid which means unfortunately I will be unable to attend Sandown on Saturday for Unibet Tolworth day,".
"It might seem a nice idea watching all the action on the television but I can tell you, in reality, it is most definitely not fun and it's fair to say I am doing lots of box walking!
"Thankfully I am not unwell and feel fine but it's important to do the right thing so you won't see me around until next week."
Constitution Hill is the one super six will have to get around
The talented five-year-old only has stablemate Jonbon ahead of him in the Supreme Novices' Hurdle betting and created a huge stir on his debut under rules over the course and distance at Sandown last month. Henderson, meanwhile, will be after a record sixth Tolworth success.
Paul Nicholls, no slouch himself, has won the Grade 1 contest four times, but the Don of Ditcheat has not struck gold since Breedsbreeze won the 2008 renewal.
Nicholls' entrant is Mr Glass, who finished fourth on his Newbury debut and then notched four straight wins in two bumpers and two novice hurdles.
Datsalrightgino rolls off the tongue for Jamie Snowden and also goes for Tolworth glory, being two from two over obstacles following wins at Fontwell in November and Cheltenham in December.
Ryan Potter is hoping for some magic from Jetoile, another entry stepping up in grade, after modest triumphs at Chepstow and Leicester.
Gary Moore's Ascot second Shallwehaveonemore and Dr Richard Newland's hurdling debutant Whizz Kid add depth to the bijou field.
Newland's charge is a multiple winner on the Flat in Germany and the Doctor is excited ahead of his British bow.
He said: "We're throwing him in at the deep end a little bit, but there's only six runners and we thought it was worth a go.
"He has some high-class form on the Flat. There's some good horses in the race on Saturday, but we hope he's a pretty good horse himself.
"If he can jump round and get some experience and pick up some prize-money, we can see where we go from there."