Laguna National hosted the Singapore Masters between 2002 and 2007 and was also used for the final edition of the Ballantine's Championship in 2014, when Chile's Felipe Agular shot 28 on the back nine to win.
However, those events were held on the Masters Course and this week's inaugural Singapore Classic is on the Classic Course known locally as 'The Beast' due to the challenge of its 7420-yard layout which features 146 bunkers and undulating greens.
"It's great to be back, I've not played a tournament in Singapore for 15 years," Fox said.
"I've actually played this golf course socially with a mate who has lived here for five years.
"It's a bit funky in places, lots of slopes. It's a good golf course. It's strong, you have to hit some golf shots. You're going to get a few holes where you thought you had a good shot but you're going to get a bad lie or end up on a big slope. If you accept at the start of the week that you'll get a couple of them, you'll be fine.
"Hopefully you don't get more of your fair share of them."
Fox won twice last season and recorded four runners-up finishes as he finished second on the money list behind Rory McIlroy and the world number 30 has enjoyed an eventful start to 2023.
"I broke my driver on Saturday in Abu Dhabi and had a half-decent week until that point," Fox added. "It didn't go very well on the weekend.
"Then in Dubai I was going nicely, got a stomach bug on the Monday morning, was pretty happy just finishing. Top 20 that week was pretty good.
"Last week (in Ras Al Khaimah) the game was close but a few too many mistakes. Hopefully I can put everything together this week and dodge some of the stuff that seems to have happened at the start of this year."
Fox is the top-ranked player in a field which also includes Japan's former world amateur number one Taiga Semikawa, who will make his DP World Tour debut.
The 22-year-old made headlines last year when he became the first amateur to win the Japan Open in its 95-year history.
There is winning in style and there is @FelipeAgui doing this in 2014 ð&³2;#SingaporeClassic | #TourArchive pic.twitter.com/JIq7JO4BZA— DP World Tour (@DPWorldTour) February 8, 2023