The hosts have dominated the biennial event since its inception, winning nine and tying one of the last 10 meetings since 2000 and on paper have by far the strongest team, with five of the world's top-10 players.
However, Stricker was a member of the team which was on the wrong end of Europe's 'Miracle at Medinah' in 2012 - when the US needed just four points from 12 singles matches to win but were overwhelmed by Jose Maria Olazabal's side's surge on Sunday.
"We learned from the 2012 Ryder Cup team and how we had this opportunity to win the Ryder Cup at Medinah, a four-point lead going into Sunday, and we didn't take enough time, really or do the right things," said the 55-year-old, who exorcised those demons as captain in a record 19-9 victory last year.
"We just didn't think that through enough probably so when we went to work last Saturday of the Ryder Cup at Whistling Straits we put in a lot of time and we made sure that we got that right.
"We put the guys in the place where we thought they should be, knowing kind of the past history of what the Europeans did.
"There's no complacency here at all. These guys know that over a course of 18 holes, anybody can beat anybody at this level.
"Our guys are ready. There's not one of them that isn't taking this very seriously."
The same is true of the International side, particularly Adam Scott who is making his 10th appearance in the event - second only to Phil Mickelson in the all-time list - but is yet to taste victory.
Vice-captain Geoff Ogilvy admits his compatriot is desperate to end that winless run.
"He really, really wants this. Can you imagine?," said his fellow Australian.
"It sucks to lose these things. You've seen us mope in here and mope out of here, and you see how fun it is for the team when they win.
"It's not very fun to lose these things, and he's done it nine times. It's brutal. You're just compounding sort of frustration."