Following arrival in Karachi, paceman Sheldon Cottrell, Roston Chase and Kyle Mayers had all tested positive.
Subsequently wicketkeeper Shai Hope, spinner Akeal Hosein and all-rounder Justin Greaves also returned positive results, along with assistant coach Roddy Estwick and physician Akshai Mansingh.
As a result, it was agreed the one-day schedule would be rearranged for early June 2022.
A joint statement from the Pakistan Cricket Board and Cricket West Indies read: "On Thursday morning and as part of the PCB COVID-19 Protocols, Rapid Antigen tests were conducted on the remaining 15 West Indies players and six-player support personnel.
"All 21 members of the West Indies touring party have returned negative test results.
"However, taking into consideration both the teams' welfare as well as limited resources in the West Indies side for the ODIs, it has been agreed that the series, which forms part of the ICC Men's Cricket Word Cup Super League, will be postponed and rescheduled for early June 2022.
"This will provide the West Indies with an equal opportunity to field their best available players for the World Cup qualification matches."