The Irish superstar made history in a fight which was the first female contest to headline Madison Square Garden in its 140-year history.
A two-division world champion, and the current undisputed champion at lightweight, who can challenge Taylor next?
Below, we take a look at five possible opponents.
The Northampton star is the current unified super lightweight champion and is set to fight in an undisputed clash against Kali Reis at the end of the year.
The pair have previously been linked to a fight but according to Cameron, she isn't on Taylor's radar.
Cameron fights at one weight class above and if Taylor could become a three-division world champion then it would solidify her status as the greatest female fighter of all-time in many people's eyes.
It would also deliver big numbers on DAZN and be a lucrative one for Taylor who could have a homecoming bout in Dublin in front of thousands.
The American is undefeated from 17 bouts and is the unified champion at junior lightweight.
And Mayer - who holds the IBF and WBO titles - is open to moving up in weight to face Taylor.
"Yes, I would love to fight Katie Taylor. She's done so much for the sport, she's been around since I first started so If I can't get the big fights that I want at 130lbs, yeah I'm going to absolutely move up."
At lightweight, this would provide an intriguing battle and considering Matchroom's ability to work alongside Top Rank, it wouldn't be a hard fight to make.
Jonas became world champion in her third attempt by winning the WBO title although it was at junior middleweight.
The former Team GB star has fought Taylor twice in her career - the first being a defeat in the amateurs and the second last year.
While she was on the receiving end of a points defeat, it was a Fight of the Year contender and considering both styles, it would be another barnburner.
Another potential rematch for Taylor.
The pair collided in 2017 and Taylor was victorious, outpointing the American to retain the WBA lightweight title.
Since losing to Taylor, McCaskill has reinvented herself and is on a six-fight winning streak, including world title wins at super lightweight and welterweight.
The notable wins are against Cecilia Braekhus to become undisputed champion at welterweight. She won both of them on points in 2020 and 201 to become the only fighter to defeat the Norwegian in her 38-fight career.
The pair could have another rematch following this weekend - and with the media attention it got, it could become an even bigger fight.
One idea for DAZN this time around could be to make it an all-female card - the first of its kind to take place at MSG or an iconic venue in the States.
With Taylor only winning by split decision, Serrano will be eager to push for a rematch, and with the first fight producing a blockbuster clash there will be plenty of interest in making it happen.