Demetrius Andrade is an undefeated two-division world champion who has made five successful defences of his middleweight world crown.
All five wins have come against European opponents, including Irish duo Luke Keeler and Jason Quigley as well as Wales' Liam Williams.
A scheduled fight with Billy Joe Saunders never came into fruition a couple of years ago and despite his impressive skills inside the ring, Andrade continues to chase a 'super-fight'.
Below, we take a look at five possible big-name opponents he could fight in 2022.
The middleweight legend is in the final couple of fights in his iconic career and is set to face Ryota Murata in a unification next.
GGG - whose only defeat has come from a controversial fight against Canelo Alvarez - is unlikely to face the Mexican again with Canelo focusing on higher weight classes at light heavyweight and cruiserweight.
Should Golovkin add the WBA belt to his IBF title, he may look to clean up the rest of the 160lb division.
Andrade would be an easy fight to make. Both are promoted by Matchroom Boxing and both are in deals to exclusively fight on DAZN. A fight could be made around October or November time.
According to Chris Mannix, this is the biggest fight to make in boxing. While we don't agree with him - neither does anyone else in boxing - it is a mouth-watering showdown with there being needle between the two Americans.
Charlo is unbeaten in 32 bouts and like Andrade, has won world championships in two divisions.
He has also made five successful world title defences and his standout victory was retaining the WBC title against Sergiy Derevyanchenko in 2020.
However, boxing politics could deny fans of a possible unification with Premier Boxing Champions [Al Haymon] and Matchroom Boxing [Eddie Hearn] not on good terms.
Chris Eubank Jr
The British star has his heart set on challenging for world honours. First he will take on Liam Williams in February but a victory will put him in the frame to challenge for one of the titles.
Golovkin is the target for Eubank but promoter Kalle Sauerland exclusively told Planet Sport that Andrade could be next for him having previously entered negotiations with the southpaw last year.
Eubank's marketability in the UK would help develop Andrade's ability to a new market and judging by his previous two defeats to Billy Joe Saunders and George Groves, he will fancy his chances of prevailing.
Billy Joe Saunders
In 2018, the pair were set to face each other before Billy Joe Saunders failed a drugs test. He would relinquish his WBO title and Andrade defeated Walter Kautondokwa for the vacated belt.
The only problem is the future of Saunders. After an orbital bone fracture in his defeat to Canelo Alvarez, it is unclear if the southpaw will return.
He has made it clear on social media that if the money is right then he will make a comeback for one more fight. There is a history of bad blood between Saunders and Andrade but probably not enough for Saunders to do a 12-week camp for.
Ejected out of Canelo's press conference after his win over Billy Joe Saunders, Andrade did his best to force a fight against the Pound for Pound star.
Alvarez laughed in his face, told him to 'get the f**k outta here' and has never mentioned his name since. It's fair to say there is no demand for this fight whatsoever.
It also doesn't help Andrade that Canelo is considering a fight at cruiserweight - three divisions higher than his current fighting weight. "Boo Boo" would have to do something extraordinary to earn a shot at boxing's king.