It's going to be another epic NFL season in 2022 as the Los Angeles Rams look to defend their Super Bowl title against a host of improving challengers.
We've got some stellar match-ups during the season and some huge events with again an extended 17-game season taking place over 18 weeks of action.
Three more games will light up Thanksgiving in the USA, while five more NFL International Series games will spread the word around the globe - including a first trip to Germany.
We've also got a Christmas Day triple-header of action so you can unwrap your presents and get stuck into some gridiron action as the cold turkey sandwiches go down.
Here's the highlights of the new 2022 NFL season.
The big kick-off
Buffalo Bills @ Los Angeles Rams (Thursday September 8)
What a way to start the season! The well-fancied Buffalo Bills visit the defending champions in the same building they lifted the Lombardi Trophy back in February.
Josh Allen versus Matthew Stafford, the return of Von Miller, it all adds up to an incredible opening kick-off game for the 2022 season.
Week One also includes a certain Russell Wilson returning to Seattle in his first game with the Denver Broncos. The schedule makers have gone all-in to start the campaign.
NFL International Series - five more games outside the USA
The NFL is going full-throttle in spreading the game this season with five games being staged internationally - including a first ever regular season game in Germany.
Bayern Munich's Allianz Arena will play host to Tom Brady and the Tampa Bay Buccaneers, while there are three more games heading to London.
Finally, the Green Bay Packers will complete the full set of 32 NFL teams to have played in London as they make the trip over to Tottenham.
The iconic Azteca Stadium in Mexico City is also holding a game, and a big one too as divisional rivals Arizona and San Francisco clash.
NFL International Series schedule:
Minnesota Vikings @ New Orleans Saints (Tottenham, October 2)
New York Giants @ Green Bay Packers (Tottenham, October 9)
Denver Broncos @ Jacksonville Jaguars (Wembley, October 30)
Seattle Seahawks @ Tampa Bay Buccaneers (Munich, November 13)
San Francisco 49ers @ Arizona Cardinals (Mexico City, November 21)
Thanksgiving turkey day triple
The NFL and Thanksgiving go hand-in-hand, and it just wouldn't be Thanksgiving without three gridiron games to feast on along with the turkey and all the trimmings.
As is tradition, the Detroit Lions get America's favourite holiday underway with their early game, and this year they'll face a tough one against the Buffalo Bills.
The Dallas Cowboys then take up their spot as Thanksgiving Day game hosts, in a move that saw them become America's Team.
NFL schedule makers have gone traditional here and given Dallas a divisional battle against the New York Giants - these games are always big-hitters.
To round us off, we have the late game which this year comes from Minnesota as the Vikings host the New England Patriots.
Week 16 - Christmas Day triple header
There's no escaping the NFL at Christmas time, with a bumper Festive schedule this year including a first for the NFL with three games being staged on Christmas Day - challenging the usual stronghold of the NBA.
With December 25 on a Sunday, the NFL is taking advantage of the captive audience by recreating their Thanksgiving spectacular with a triple header.
How else would you rather spend your Christmas Day then in the company of Aaron Rodgers, Tom Brady, Russell Wilson, Matthew Stafford and Kyler Murray.
The Green Bay Packers will wake up on Christmas morning in Miami as they face the Dolphins in the early game, followed by the Denver Broncos visiting the Los Angeles Rams before Brady's Buccaneers visit the Arizona Cardinals.
In what is a festive fiesta of football, Week 16 starts on Thursday December 22 with the Jacksonville Jaguars at the New York Jets, before 11 games to occupy your Christmas Eve on Saturday.
Just for good measure, there's a Boxing Day game as the Indianapolis Colts host the Los Angeles Chargers.
When and where is the next Super Bowl?
All roads lead to Glendale in Arizona, just outside Phoenix, this season as Super Bowl LVII will be staged at State Farm Stadium - the home of the Cardinals - on Sunday February 12.
No pressure on Kyler Murray and the Cards but the hosts have won the last two Super Bowls...
There will be 14 teams again making the playoffs, with just the top seed from the NFC and the AFC getting a first-round bye, although neither top seed made it all the way last season.
Wildcard weekend takes place on January 14-16 with six games spread across the weekend involving the sides finishing from second to seventh. Seeds two, three and four hosting seeds seven, six and five respectively.
The Divisional round is set for January 21-22 and the Championship Games, to decide who goes to the Super Bowl, will be played on January 29.