Stade Français produced a powerful display to hammer Grenoble 43-30 and become the first team to win at the Stade des Alpes this season.
Following back-to-back encounters with Leinster, there are six changes to the side for Harlequins against Newcastle.
Over 28,000 supporters are expected at the Ricoh Arena this Sunday for Wasps first game at their new home against London Irish.
The Saints line-up that will start against Leicester shows a handful of changes as the Premiership returns with a fierce derby.
Bath have to announced that the powerful back-row trio of Matt Garvey, Leroy Houston and Guy Mercer have renewed their contracts.
Leicester lock Graham Kitchener is settling into a rhythm alongside Brad Thorn and admits he is enjoying playing with a legend.
Saracens boss Edward Griffiths has called for the salary cap to be scrapped as it will "kill any hope of growth."
Although Tom Varndell is keen to play at the Olympics his next challenge is to ensure Wasps begin life in Coventry with a bang.
Will Genia's long-term future looks set to be in France, despite the Australian scrum-half signing a pre-contract with Bath.
Racing Métro owner Jacky Lorenzetti admits that turning down the chance to sign Jonny Wilkinson was a harsh lesson for the club.
All Blacks coach Steve Hansen has cleared star centre Sonny Bill Williams to resume his boxing career in January.
Arnaud Héguy will captain Grenoble when Stade Français visit the Stade des Alpes in the Top 14 on Friday.
Zebre replacement wing David Odiete, has been suspended for two weeks following his sending off against Gloucester on Saturday.
The IRFU and Leinster have announced that Mike Ross has signed a new one-year contract to stay in Ireland until June 2016.
Premiership clubs Bath and London Irish are both chasing Wales fly-half Rhys Priestland ahead of next season.
Ireland fly-half Jonathan Sexton has been ruled out until February 14 next year following a series of headaches and nausea.
Leinster make seven changes in total from the team which accounted for Harlequins in the Champions Cup last weekend.