Harlequins moved five points ahead of Gloucester after they beat the Cherry and Whites 29-26 at the Stoop on Saturday.
Wales prop Adam Jones looks set to leave Cardiff Blues at the end of the season, with the region not set to offer him a new deal.
Edinburgh's wing options look set for a revamp for next season, with Tim Visser being linked with a move to Harlequins.
Harlequins boss Conor O'Shea defended his players after seeing them hang on against London Irish to end a difficult run of results.
Northampton boss Jim Mallinder has made just one chsnge to his starting XV for Friday's clash with Harlequins at Franklin's Gardens.
Harlequins have announced that back-rower Netani Talei has signed with the club for the remainder of the season.
Harlequins boss Conor O'Shea has made two changes to his starting XV for Saturday's clash with Exeter Chiefs at the Stoop.
Harlequins have announced that loosehead Mark Lambert has signed an extension to his deal, which will keep him at the club until 2017....
Harlequins winger Charlie Walker has signed a new deal with the club keeping him at the Stoop until 2017.
Wasps and Harlequins will face off against each other for the fourth time already this season at the Ricoh Arena on Sunday.
Nick Evans will start for Harlequins as they look to keep their LV= Cup hopes alive at home to Bath at the Stoop.
Harlequins have been dealt a blow with the news that tighthead prop Will Collier will miss the rest of the season due to a knee injury....
Conor O'Shea admits Harlequins were left to rue last week's loss at home to Wasps as they went out of Europe despite a win in Castres....
James Haskell is hitting peak form according to Dai Young after the flanker helped Wasps to a vital victory away at Harlequins.
Harlequins outscored Leicester Tigers four tries to none to pick up a much-needed 32-12 victory in the Premiership on Saturday.
Veteran Harlequins number eight Nick Easter has added his own voice to calls of a return to the England side for the upcoming Six Nations....
Harlequins director of rugby Conor O'Shea has backed in-form number eight Nick Easter for an England recall in their World Cup challenge....